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Transfection:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), SDS Page:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Western Blot:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Acetylene Reduction Assay:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Control:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Activity Assay:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Concentration Assay:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Expressing:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Clinical Proteomics:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Drug discovery:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Inhibition:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Permeability:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), Enzyme-linked Immunosorbent Assay:Article Title: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Article Snippet: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(17)30003-3 DOI: doi:10.1016/j.bbalip.2017.01.003 Reference: BBAMCB 58101 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 25 October 2016 Revised date: 3 January 2017 Accepted date: 12 January 2017 Please cite this article as: Jacqueline Kalms, Swathi Banthiya, Etienne Galemou Yoga, Mats Hamberg, Hermann-Georg Holzhutter, Hartmut Kuhn, Patrick Scheerer, The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity, BBA - Molecular and Cell Biology of Lipids (2017), doi:10.1016/j.bbalip.2017.01.003 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid Article Snippet: Materials—Arachidonic acid, 11R-HETE, and 15S-HETE were pur- chased from Article Title: Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer. Article Snippet: Article Title: Strata movement and stress evolution when mining two overlapping panels affected by hard stratum Article Snippet: 15s-HpETE and Article Title: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Article Snippet: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer PII: S1388-1981(16)30222-0 DOI: doi: 10.1016/j.bbalip.2016.08.002 Reference: BBAMCB 58023 To appear in: BBA - Molecular and Cell Biology of Lipids Received date: 19 May 2016 Revised date: 29 July 2016 Accepted date: 3 August 2016 Please cite this article as: Swathi Banthiya, Jacqueline Kalms, Etienne Galemou Yoga, Igor Ivanov, Xavi Carpena, Mats Hamberg, Hartmut Kuhn, Patrick Scheerer, Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa, BBA - Molecular and Cell Biology of Lipids (2016), doi: 10.1016/j.bbalip.2016.08.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. 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Article Title: Stabilization and improved activity of arachidonate 11S-lipoxygenase from proteobacterium Myxococcus xanthus Article Snippet: Article Title: Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid Article Snippet: Article Title: Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Article Snippet: Standards of ARA and LA derivatives: Thromboxane B2 (TXB2), Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), 13S-HODE (13S-hydroxy-9Z,11E-octadecadienoic acid), 9S-HODE (9S-hydroxy-10E, 12Z-octadecadienoic acid), 15S-HETE (15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid), 12S-HETE (12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid), 5-oxoETE (5-Oxo-eicosatetraenoic acid), 5-HETE (5-hydroxyeicosatetraenoic acid), 5(S),6(R)-lipoxin-A4 (5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid), 5(S),6(R)15(R)-lipoxin-A4, (5(S),6(R),15(R)-trihydroxy 7E,9E,11Z,13E-eicosatetraenoic acid), |
